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KMID : 0361620200550040331
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Journal of the Korean Orthopaedic Association
2020 Volume.55 No. 4 p.331 ~ p.337
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Prognostic Indicators of Extremity Liposarcoma
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Park Kee-Young
Kim Jeung-Il
Lee In-Sook
Song You-Seon
Choi Kyung-Un
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Abstract
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Purpose: The aim of this retrospective study was to define the prognostic factors for liposarcoma to aid in the selection of effective treatments.
Materials and Methods: This study analyzed 41 cases out of 45 cases diagnosed with and treated for liposarcoma 2002 to 2015; 4 cases of well-differentiated liposarcoma were excluded. The effects of sex, age, site, stage, and histological classification on survival were analyzed retrospectively. For 28 cases diagnosed with myxoid liposarcoma, additional analysis was performed after the inclusion of round cell components.
Results: The mean age at diagnosis was 52.05 years (range 25?82 years) and the average follow-up period was 63.7 months. The disease-free survival rate was 43.2%. Most factors, including sex and age, were not significantly associated with the survival rate. On the other hand, the stage (Musculoskeletal Tumor Society stage) was significantly associated with the survival rate. The survival rate of patients with myxoid liposarcoma was 69% and the local recurrence and metastasis results varied according to the presence of round cells.
Conclusion: The stage of liposarcoma and the sex of the patient were found to be effective factors for prognosis. When planning the treatment for liposarcoma, the treatment outcome for liposarcoma differs according to several prognostic factors.
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KEYWORD
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liposarcoma, myxoid liposarcoma, round cell liposarcoma
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